Xarelto, Coupled with Average Painkillers, Leads to Dangerous Results

A study released on November 18, 2014 in the medical journal Annals of Internal Medicine determined that patients who took a combination of an anticoagulant, like Xarelto or Pradaxa, with nonsteroidal anti-inflammatory drugs (NSAID), such as Advil, Motrin, and Aleve, had a significantly increased risk of severe bleeding events. While all blood thinning drugs bear bleeding risks, Xarelto especially lacks reversal agents to stop this harmful side effect—which is exacerbated by the use of common painkillers. Performed in Denmark on over 150,000 atrial fibrillation patients taking blood-thinning drugs, the study found that after just two weeks of taking a combination of these drugs, there was an increased risk of severe bleeding and that side effects were determined to be dose-specific—highlighting the dangers that these anticoagulant drugs can cause.

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