One-Third of Hospital Xarelto/Pradaxa Prescriptions Too High

A new study presented by Fairleigh Dickinson University School of Pharmacy researchers at a Society of Critical Care Medicine meeting in December 2014 has determined that one-third of patients prescribed a blood-thinner in the intensive care unit (ICU) of a hospital received dosages that were too high. These newer blood-thinners, including Xarelto and Pradaxa, were incorrectly dosed to patients due to failures to account for kidney function problems, which can affect the body’s filtering of the drug and consequently increase the risk of bleeding. This side effect is particularly significant in the new generation of anticoagulents, as no antidote exists should a bleeding event occur—leaving doctors with no recourse to treat patients suffering potentially fatal blood loss.

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